Rheumatoid Arthritis Research
Dr. Miriam Shelef is an immunologist and a rheumatologist with a research program focused on better understanding the pathophysiology of rheumatoid arthritis to inform the development of novel biomarkers and treatments.
Pathophysiology of Autoimmune Disease
Dr. Shelef's research aims to solve the mysteries of how and why systemic autoimmunity develops and persists in order to guide the discovery of better clinical tests and improved treatments. Her lab has two major research directions.
- Define the role of citrullination and the citrullinating peptidylarginine deiminase enzymes in immunity, inflammation, and rheumatoid arthritis
- Discover new autoantibody targets as well as novel features of antibody and autoantibody reactivity in rheumatoid arthritis, COVID-19, systemic lupus erythematosus, and other autoimmune and inflammatory diseases.
Research Team
Sirtaij Arora
Undergraduate Student
Braedon Krisko
Undergraduate Researcher
Undergraduate Researcher
Researcher
Research Intern
Adam Titi
Undergraduate Researcher
Alumni
- Alumni
Ryan Adyniec
Past Position: Undergraduate student
Next Position: Impact Networking
Maya Amjadi
Past Position: Graduate student (MSTP)
Next Position: Medical student, University of Wisconsin MSTP
Janna Bashar
Past Position: Graduate student
Next Position:
Mandar Bawadekar, PhD
Past Position: Postdoctoral fellow
Next Position: Senior scientist at Invenra
Amy Bier
Past Position: Study coordinator and research assistant
Next Position: Medical student, Stritch School of Medicine of Loyola University Chicago
Michael Denny, PhD
Scientist
Tobias Donlon
Past Position: Study coordinator and research assistant
Next Position: Medical student, University of Minnesota Medical School
Lauren Fahmy
Past Position: Undergraduate student
Next Position: Medical student at Columbia University, Vagelos College of Physicians and Surgeons
Christopher Glover
Past Position: Study coordinator and research assistant
Next Position: Medical student, University of Wisconsin School of Medicine and Public Health
Srishti Gupta
Past Position: Undergraduate student
Next Position: Associate clinical research coordinator at Rush University
Caitlyn Holmes
Past Position: Graduate student
Next Position: Postdoctoral fellow, University of Michigan
Aisha Mergaert
Past Position: Graduate student
Next Position: Postdoctoral fellow, University of Wisconsin
Maxwell Parker
Past Position: Research assistant
Next Position: JangoBio
Chloe Peyton
Past Position: Undergraduate student
Next Position: Medical student, University of Minnesota Medical School
Nicole Rademacher
Past Position: Study coordinator and research assistant
Next Position: Medical student at Medical College of Wisconsin
Ryan Rebernick
Past Position: Undergraduate student
Next Position: MD/PhD student at the University of Michigan
Rebecca (Daeun) Shim
Past Position: Study coordinator and research assistant
Next Position: Master's student at Rush University
Zihao Zheng
Past Position: Graduate student
Next Position: Data scientist at Google
Funding Support
Dr. Shelef's research has been supported by the Rheumatology Research Foundation, the NIH NIAMS, the Wisconsin Partnership Program, the Doris Duke Charitable Foundation, the Congressionally Directed Medical Research Programs, and the University of Wisconsin.
My Green Lab Certified
The Shelef Lab is a Green Level Certified Lab for outstanding work in reducing the environmental impact of laboratory space and successful completion of the My Green Lab Certification Program.