Our research interests over the past three decades have included the study and prevention of nosocomial infections, the clinical application of novel agents for the treatment of septic shock, and the epidemiology and prevention of infections caused by antimicrobial resistant pathogens.
Our research of novel technology for the prevention of intravascular catheter-related bacteremia has shown that use of better cutaneous antisepsis at the time of catheter insertion, use of antimicrobial-impregnated central venous catheters in high risk patients and the use of chlorhexidine-impregnated gauze dressing at catheter insertion sites all are effective methods of protecting patients from the morbidity of these infections.
Similar work in the study of catheter-associated urinary tract infections (CAUTIs) has shown that most bateriuric patients with foley catheters do not develop symptomatic infections, although these infections generate significant healthcare costs and form a reservoir from which resistant bacteria commonly emerge. Our recent research on the use of novel technology for the prevention of nosocomial infections has shown that the use of antimicrobial-impregnated foley catheters significantly reduces the rates of bacteruria among hospitalized patients who are catheterized for short periods of time.
We continue to investigate novel tools and techniques for the treatment and prevention of infections among hospitalized patients.
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